Formulation and evaluation mouth dissolving tablets of Tramadol HCL - Softcover
According to United States Pharmacopoeia, the orodispersible tablets may be defined as solid dosage form containing medicinal substance or active ingredient which disintegrates rapidly within a matter of seconds when placed upon the tongue. This means that the tablets dissolve or disintegrate in the oral cavity without use of water. In this regard, the tablets need to improve disintegration time, dispersion time, drug release studies, bioavailability and patient compliance and also need to mask the bitter taste of the drug and to maintain the drug stable at accelerated condition i.e. 40C/75% RH up to 6 months period as per ICH guidelines. Tramadol HCl is centrally acting synthetic opioid analgesic for the treatment of moderate to severe pain and is readily soluble in water. The half life of the drug is around 5.5 hours. The MDT's place a major role for rapid onset of action for geriatrics, pediatrics and the patients who have less access of water. The drug itself having bitter taste, so the present authors developed mouth dissolving tablets of tramadol HCl with the aim to mask the bitter taste of the drug, to minimize the disintegration time and improve the drug release rate.
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About the Author:
My self Raja Sridhar Rao. P working as Associate Professor in Chaitanya college of Pharmaceutical Education and Research, Warangal, Telangana, India. I have more than 10years of experience in teaching and have 14 national and international publications till date.
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2015
- ISBN 10 3659766917
- ISBN 13 9783659766916
- BindingPaperback
- Number of pages60
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Formulation and evaluation mouth dissolving tablets of Tramadol HCL
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -According to United States Pharmacopoeia, the orodispersible tablets may be defined as solid dosage form containing medicinal substance or active ingredient which disintegrates rapidly within a matter of seconds when placed upon the tongue. This means that the tablets dissolve or disintegrate in the oral cavity without use of water. In this regard, the tablets need to improve disintegration time, dispersion time, drug release studies, bioavailability and patient compliance and also need to mask the bitter taste of the drug and to maintain the drug stable at accelerated condition i.e. 40 C/75% RH up to 6 months period as per ICH guidelines. Tramadol HCl is centrally acting synthetic opioid analgesic for the treatment of moderate to severe pain and is readily soluble in water. The half life of the drug is around 5.5 hours. The MDT's place a major role for rapid onset of action for geriatrics, pediatrics and the patients who have less access of water. The drug itself having bitter taste, so the present authors developed mouth dissolving tablets of tramadol HCl with the aim to mask the bitter taste of the drug, to minimize the disintegration time and improve the drug release rate. 60 pp. Englisch. Seller Inventory # 9783659766916
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Formulation and evaluation mouth dissolving tablets of Tramadol HCL
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ISBN 13: 9783659766916
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Formulation and evaluation mouth dissolving tablets of Tramadol HCL
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ISBN 13: 9783659766916
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - According to United States Pharmacopoeia, the orodispersible tablets may be defined as solid dosage form containing medicinal substance or active ingredient which disintegrates rapidly within a matter of seconds when placed upon the tongue. This means that the tablets dissolve or disintegrate in the oral cavity without use of water. In this regard, the tablets need to improve disintegration time, dispersion time, drug release studies, bioavailability and patient compliance and also need to mask the bitter taste of the drug and to maintain the drug stable at accelerated condition i.e. 40 C/75% RH up to 6 months period as per ICH guidelines. Tramadol HCl is centrally acting synthetic opioid analgesic for the treatment of moderate to severe pain and is readily soluble in water. The half life of the drug is around 5.5 hours. The MDT's place a major role for rapid onset of action for geriatrics, pediatrics and the patients who have less access of water. The drug itself having bitter taste, so the present authors developed mouth dissolving tablets of tramadol HCl with the aim to mask the bitter taste of the drug, to minimize the disintegration time and improve the drug release rate. Seller Inventory # 9783659766916
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Formulation and evaluation mouth dissolving tablets of Tramadol HCL
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Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Ponugoti Raja Sridhar RaoMy self Raja Sridhar Rao. P working as Associate Professor in Chaitanya college of Pharmaceutical Education and Research, Warangal, Telangana, India. I have more than 10years of experience in teaching and hav. Seller Inventory # 158605233
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