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In Paradigms Lost, he presents the evidence for yes and no answers to each question as though in a trial by jury, with witnesses arguing for the prosecution and defense, then a summary of the evidence and a verdict. Paradigms Regained takes the same questions to an appeals court, summarizes the evidence from the "trial" and introduces new evidence from the intervening decade.
Casti's goal is to show how science works, how "the single most characteristic feature of science is that its conclusions are tentative." So in three cases he now reaches a ruling of "appeal upheld," overturning his previous verdicts. In fact, the only one truly overturned is his conclusion of "not proven" to the question about the genetic determination of human behavior: he thinks the evidence for "yes" has become much stronger. In the cases of the origin of life and the existence of a Real World, he has kept the same one-word answers but now favors different mechanisms.
Together, the two books are good illustrations of how science looks at the questions that most interest nonscientists and of how scientific knowledge builds and changes. They make excellent maps to the borders between science and philosophy, science and religion, and science and pseudoscience. --Mary Ellen Curtin
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