UPLC analysis of keto-analogues of essential amino acid calcium salt - Softcover

9783639662481: UPLC analysis of keto-analogues of essential amino acid calcium salt
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Alpha keto-analogues of valine, leucine, isoleucine, methionine, phenyl-alanine, and (in one instance) tryptophan and histidine, along with the remaining essential amino acids, are used to treat severe renal failure (Chronic Uremia). Mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. The analytical method for determination of calcium salts of some alpha keto acid analogues using ultra performance liquid chromatography was developed and validated as per the ICH guideline in terms of Specificity, Linearity and range, Accuracy, Precision, Limit of Detection, Limit of Quantification, Robustness and Stability. The method has been proved as a high throughput screening as it has analysis time of only 8.0 minutes with very good sensitivity and resolution; this method is applicable for bulk drug as well as in pharmaceutical dosage form

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The Author has Done Masters and Doctorate from Saurashtra University, Rajkot India, which is one of the premier institute of chemistry in India.The author has more then eight years experience of of pharmaceutical research and development.

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  • PublisherScholars' Press
  • Publication date2014
  • ISBN 10 3639662482
  • ISBN 13 9783639662481
  • BindingPaperback
  • Number of pages52

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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Alpha keto-analogues of valine, leucine, isoleucine, methionine, phenyl-alanine, and (in one instance) tryptophan and histidine, along with the remaining essential amino acids, are used to treat severe renal failure (Chronic Uremia). Mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. The analytical method for determination of calcium salts of some alpha keto acid analogues using ultra performance liquid chromatography was developed and validated as per the ICH guideline in terms of Specificity, Linearity and range, Accuracy, Precision, Limit of Detection, Limit of Quantification, Robustness and Stability. The method has been proved as a high throughput screening as it has analysis time of only 8.0 minutes with very good sensitivity and resolution; this method is applicable for bulk drug as well as in pharmaceutical dosage form 52 pp. Englisch. Seller Inventory # 9783639662481

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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Alpha keto-analogues of valine, leucine, isoleucine, methionine, phenyl-alanine, and (in one instance) tryptophan and histidine, along with the remaining essential amino acids, are used to treat severe renal failure (Chronic Uremia). Mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. The analytical method for determination of calcium salts of some alpha keto acid analogues using ultra performance liquid chromatography was developed and validated as per the ICH guideline in terms of Specificity, Linearity and range, Accuracy, Precision, Limit of Detection, Limit of Quantification, Robustness and Stability. The method has been proved as a high throughput screening as it has analysis time of only 8.0 minutes with very good sensitivity and resolution; this method is applicable for bulk drug as well as in pharmaceutical dosage form. Seller Inventory # 9783639662481

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