An Overview of Genetic Factors and Environmental Triggers in the Pathogenesis of Tourette's Syndrome (Neuroscience Research Progress) - Softcover

9781616687489: An Overview of Genetic Factors and Environmental Triggers in the Pathogenesis of Tourette's Syndrome (Neuroscience Research Progress)
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Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterized by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease etiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signaling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility.

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  • PublisherNova Biomedical
  • Publication date2010
  • ISBN 10 1616687487
  • ISBN 13 9781616687489
  • BindingPaperback
  • Edition number1
  • Number of pages59

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Book Description Paperback. Condition: new. Paperback. Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signalling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility. Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. This book discusses the state of genetic studies in TS susceptibility. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Seller Inventory # 9781616687489

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