Cancer Chemotherapy and Biotherapy: Principles and Practice (Chabner, Cancer Chemotherapy and Biotherapy) - Hardcover

9781605474311: Cancer Chemotherapy and Biotherapy: Principles and Practice (Chabner, Cancer Chemotherapy and Biotherapy)

Hardcover

ISBN 10: 1605474312 ISBN 13: 9781605474311

Publisher: Lippincott Williams & Wilkins, 2010

Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations.

This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised.

A companion website includes the fully searchable text and an image bank.

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Review:

New England Journal of Medicine, Volume 18, Issue 355 -- "The editors have taken on the Herculean task of melding chemotherapy and biologic therapy, with an emphasis on clinical relevance. To a great degree, they have accomplished their goal. The chapters are up to date, considering the rapid changes in the field. There is extensive use of illustrations and tables, and summary tables in each chapter reinforce the central themes. The discussion of antibody therapy provides an excellent overview of the current state of functional mechanisms. This textbook will continue to be a resource for clinical oncologists, and it remains one of the essential readings for medical oncologists in training. The editors and contributors should be complimented on the results of their labors, which improve on their previous exceptional efforts."

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