The Synaptic Organization of the Brain ISBN 13: 9780195062557

The Synaptic Organization of the Brain - Hardcover

9780195062557: The Synaptic Organization of the Brain
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The third edition of The Synaptic Organization of the Brain continues the tradition of earlier editions in focusing on the principles underlying the organization of neurons and synapses into functional circuits within the best-studied regions of the brain: autonomic ganglia, spinal cord, olfactory bulb, retina, cerebellum, thalamus, basal ganglia, olfactory cortex, hippocampus, and neocortex. To ensure authoritative coverage of each area, the chapters have been revised by leading researchers. Nevertheless, as in past editions, each chapter follows the same format: neural elements, synaptic connections, basic circuits, physiological properties, neurotransmitters, and dendritic properties. In addition, each chapter now has a concluding section which discusses functional implications. This organization gives a logical structure to the description of each region, and greatly facilitates comparisons between regions and identification of common principles. Highlights include the first comprehensive attempt to incorporate intrinsic excitable membrane properties into neural circuits throughout the brain, the latest experimental results from patch recordings, brain slices, intracellular labelling, and 3-D reconstructions of neurons and connections. The book also provides summaries of neurotransmitters, neuromodulators, second-messengers and ligand-and voltage-gated membrane channels for each brain region. Up-to-date information on mechanisms underlying development and plasticity in brain circuits is also included as are computer methods for modeling neurons and circuits as a first step toward a "biophysics of neural computation."

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About the Author:

Gordon M. Shepherd is Professor of Neuroscience, Yale University.
Review:
" ... a compact monograph that makes a real and insightful effort to integrate information from synaptic neurophysiology with that from the areas of neuroanatomy, neuropharmacology and molecular neurobiology. ... The book provides excellent reviews of fundamental concepts and current hypotheses on the synaptic organization of the brain ... a good book on a difficult subject... a necessary complement to the library of any neurosciences-oriented institution. ... I recommend it to graduate students and postdoctoral fellows trying to grasp the development of a very important area of central nervous system research. ... it is sufficiently detailed and integrative to be useful to neuroscientists and anyone interested in the field of neuronal connectivity and function. This is a helpful book and I recommend it. " Journal of Psychiatry and Neuroscience (1998)

Praise for previous editions:

"The book remains a staple, and should be on the shelf of any serious neuroscientist."--The Quarterly Review of Biology

"An excellent introduction into the principles of synaptic organization of various brain regions."--Neuroscience

"By any measure this work is a classic...It will undoubtedly take its place as one of the most significant and comprehensive commentaries of our time on structure and function of nervous tissue."--Journal of Electroencephalography and Clinical Neurophysiology

"A valuable addition to the library of individuals who call themselves neuroscientists; it is a good general reference that provides a basic understanding of the neuroanatomy, neurophysiology, and neurochemistry that underlie the organization of neurons and synapses into functional circuits. This text also would provide a good introduction to further study of any of the specific regions of the nervous system."--Journal of the American Physical Therapy Association

"By any measure this work is a classic...It will undoubtedly take its place as one of the most significant and comprehensive commentaries of our time on the structure and function of nervous tissue."--Journal of Electroencephalography and Clinical Neurophysiology

"...this book is a coherent and lucid account on the physiological significance of brain connectivity and represents a necessary complement to the library of any neurosciences-oriented institution."--Journal of Psychiatry and Neuroscience

'This is the fourth edition of a reference textbook that has served generations of neuroscientists at all levels of thier career for a quarter century. It is like a wise and trusted mentor, who is always ther for you...And certaintly, any college or university instructor who teaches neurobiology ought to read this book, for it provides a depth of knowledge and perspective that cannot be gained from a (bad) strategy of knowing the course textbook cold and staying a few chapters ahead of one's students.--ordon M. Shepherd, Contempory Psychology.

'This is the fourth edition of a reference textbook that has served generations of neuroscientists at all levels of their career for a quarter century. It is like a wise and trusted mentor, who is always there for you...And certaintly, any college or university instructor who teaches neurobiology ought to read this book, for it provides a depth of knowledge and perspective that cannot be gained from a (bad) strategy of knowing the course textbook cold and staying a few chapters ahead of one's students.--ordon M. Shepherd, Contempory Psychology.

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Other Popular Editions of the Same Title

9780195017939: The synaptic organization of the brain: An introduction

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ISBN 10:  0195017935 ISBN 13:  9780195017939
Publisher: Oxford University Press, 1974
Softcover

  • 9780192690012: Synaptic Organization of the Brain: An Introduction (Oxford medical publications)

    Oxford..., 1975
    Softcover

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